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Enzinger And Weiss Soft Tissue Tumors 6th Edition Pdf Free 64

Dermatofibrosarcoma protuberans (DFSP) is a relatively common soft-tissue tumor. A more aggressive appearing fibrosarcoma may arise in DFSP, changing its biological behavior. CD34 and apolipoprotein-D are highly expressed in DFSP, but their prognostic significance is uncertain.

enzinger and weiss soft tissue tumors 6th edition pdf free 64

Dermatofibrosarcoma protuberans (DFSP) is a low grade malignant mesenchymal tumor that typically arises in the dermis of the trunk and proximal extremities [1]. DFSP represents 1 to 6% of all soft tissue sarcomas (STS) [2, 3] and its frequency of detection slowly has increased over time [4]. DFSP is characterized by latency of initial diagnosis, slow infiltrative growth and a high rate of local recurrence if not adequately treated. Death due to metastatic disease is very rare (

DFSP is a soft tissue malignancy that often shows extensive local invasion but rarely metastasizes [14]. DFSP can lead to significant morbidity from repeated surgical excisions, but infrequently leads to death [3, 5, 6, 15, 16].

Management of soft tissue tumours around the elbow may be challenging because of their rarity and the proximity to neurovascular structures. Careful staging, histological diagnosis and treatment are essential to optimize clinical outcome. A missed or delayed diagnosis or an improperly executed biopsy may have devastating consequences for the patient.

Soft tissue tumours around the elbow are rare, with an incidence of around 3.8% of all soft tissue tumours.1 Benign soft tissue tumours occur approximately 10 times more frequently than malignant ones.2 Nevertheless, although the clinical presentation of the most frequent lesions might be straightforward, it can often be difficult to differentiate benign and reactive lesions from malignant and aggressive ones on purely clinical grounds. Thus, it is important for the clinician to be aware of the wide variety of these lesions and treat appropriately or refer to a specialist centre. When a lesion raises suspicions, it should not be only treated with excisional biopsy, as this approach might lead to errors which are difficult to remedy. Where there is doubt after initial assessment, this should prompt referral to a specialized tumour centre, where an appropriate biopsy and pre-operative and reconstructive planning should take place prior to undertaking any treatment. This article reviews the most common benign and malignant soft tissue tumours of the elbow and discusses the clinicopathological findings, imaging characteristics and current concepts of treatment.


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